Blood+ is an animated television series created by Production I.G. It premiered in Japan on October 8, 2005 on MBS/TBS, and continued with episodes every week (except on December 31, 2005) until September 23, 2006.

The series simultaneously aired on Animax, Sony's Japanese anime satellite channel, with its networks in Southeast Asia and South Asia airing the series later.

Blood+ anime is directed by Junichi Fujisaku and features original character designs by Chizu Hashii. Fifty consecutive episodes spanning throughout four distinct seasons form the anime. Each season is differentiated by opening and ending themes from a variety of artists.

It began airing in dubbed English in the United States on March 11, 2007 as part of the Adult Swim block of Cartoon Network, where it ran until its conclusion on March 23, 2008.

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